Pathogenic Mechanisms of Hypertrophic Cardiomyopathy beyond Sarcomere Dysfunction

Pathogenic Mechanisms of Hypertrophic Cardiomyopathy beyond Sarcomere Dysfunction

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disorder, affecting 1 in 500 people in the general population. Although characterized by asymmetric left ventricular hypertrophy, cardiomyocyte disarray, and cardiac fibrosis, HCM is in fact a highly complex disease with h...

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Bibliographic Details
Main Authors: Chun Chou, Michael T. Chin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
hypertrophic cardiomyopathy
pathological cardiac hypertrophy
sarcomere
cardiac myocyte
cardiac fibroblast
cardiac fibrosis
Online Access:https://www.mdpi.com/1422-0067/22/16/8933

Internet

https://www.mdpi.com/1422-0067/22/16/8933

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