A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening

A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening

<p>Abstract</p> <p>Background</p> <p>A newly identified mechanism of smooth muscle relaxation is the interaction between the small heat shock protein 20 (HSP20) and 14-3-3 proteins. Focusing upon this class of interactions, we describe here a novel drug target screening...

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Bibliographic Details
Main Authors: von Rechenberg Moritz, Peltier John M, Ahn Kwangmi, Zarembinski Thomas I, Askovich Peter S, An Steven S, Sahasrabudhe Sudhir, Fredberg Jeffrey J
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/8

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http://respiratory-research.com/content/12/1/8

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