The EMIF-AD PreclinAD study: study design and baseline cohort overview

The EMIF-AD PreclinAD study: study design and baseline cohort overview

Abstract Background Amyloid pathology is the pathological hallmark in Alzheimer’s disease (AD) and can precede clinical dementia by decades. So far it remains unclear how amyloid pathology leads to cognitive impairment and dementia. To design AD prevention trials it is key to include cognitively nor...

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Main Authors: Elles Konijnenberg, Stephen F. Carter, Mara ten Kate, Anouk den Braber, Jori Tomassen, Chinenye Amadi, Linda Wesselman, Hoang-Ton Nguyen, Jacoba A. van de Kreeke, Maqsood Yaqub, Matteo Demuru, Sandra D. Mulder, Arjan Hillebrand, Femke H. Bouwman, Charlotte E. Teunissen, Erik H. Serné, Annette C. Moll, Frank D. Verbraak, Rainer Hinz, Neil Pendleton, Adriaan A. Lammertsma, Bart N. M. van Berckel, Frederik Barkhof, Dorret I. Boomsma, Philip Scheltens, Karl Herholz, Pieter Jelle Visser
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Alzheimer’s Research & Therapy
Subjects:
Preclinical Alzheimer’s disease
Amyloid
Cognitively normal
Monozygotic twins
[18F]flutemetamol
Online Access:http://link.springer.com/article/10.1186/s13195-018-0406-7

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http://link.springer.com/article/10.1186/s13195-018-0406-7

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