Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats

Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats

Abstract Background Over 50% of acute stroke patients have hyperglycemia, which is associated with a poorer prognosis and outcome. Our aim was to investigate the impact of hyperglycemia on behavioral recovery and brain repair of delivered human adipose tissue-derived mesenchymal stem cells (hAD-MSCs...

Full description

Bibliographic Details
Main Authors: Mari Carmen Gómez-de Frutos, Fernando Laso-García, Luke Diekhorst, Laura Otero-Ortega, Blanca Fuentes, Jukka Jolkkonen, Olivier Detante, Anaick Moisan, Arturo Martínez-Arroyo, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, on behalf of RESSTORE consortium
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose tissue
Behavioral outcome
Brain repair
Experimental model
Hyperglycemia
Mesenchymal stem cells
Online Access:http://link.springer.com/article/10.1186/s13287-019-1322-x

Internet

http://link.springer.com/article/10.1186/s13287-019-1322-x

Similar Items