Identifying and understanding factors that affect the translation of therapies from the laboratory to patients: a study protocol [version 2; peer review: 2 approved]

Background: The process of translating preclinical findings into a clinical setting takes decades. Previous studies have suggested that only 5-10% of the most promising preclinical studies are successfully translated into viable clinical applications. The underlying determinants of this low success...

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Bibliographic Details
Main Authors: Manoj M. Lalu, Joshua Montroy, C. Glenn Begley, Tania Bubela, Victoria Hunniford, David Ripsman, Neil Wesch, Jonathan Kimmelman, Malcolm Macleod, David Moher, Alvin Tieu, Lindsey Sikora, Dean A. Fergusson
Format: Article
Language:English
Published: F1000 Research Ltd 2020-10-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-485/v2