Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis

The Region of D eletion 2 (RD2) of Mycobacterium tuberculosis encodes reserved antigens that contribute to bacterial virulence. Among these antigens, Rv1983, Rv1986, Rv1987, and Rv1989c have been shown to be immunodominant in infected cattle; however, their diagnostic utility has not been evaluated...

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Bibliographic Details
Main Authors: Jiazhen Chen, Qiaoling Ruan, Yaojie Shen, Sen Wang, Lingyun Shao, Wenhong Zhang
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867018305543