Cardiovascular Patterning as Determined by Hemodynamic Forces and Blood Vessel Genetics.

BACKGROUND:Vascular patterning depends on coordinated timing of arteriovenous specification of endothelial cells and the concomitant hemodynamic forces supplied by the onset of cardiac function. Using a combination of 3D imaging by OPT and embryo registration techniques, we sought to identify struct...

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Bibliographic Details
Main Authors: Gregory A Anderson, Ryan S Udan, Mary E Dickinson, R Mark Henkelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4560395?pdf=render