Hesperetin ameliorates diabetic nephropathy in rats by activating Nrf2/ARE/glyoxalase 1 pathway

Diabetic nephropathy (DN) is one of the most common diabetic complications, and alpha-carbonyl aldehydes and their detoxicating enzyme glyoxalase 1 (Glo-1) play vital roles in pathogenesis of diabetic complications. The aim of this study was to evaluate the renoprotective effects of hesperetin again...

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Bibliographic Details
Main Authors: Ya-Jing Chen, Li Kong, Zhuang-Zhuang Tang, Yu-Meng Zhang, Yue Liu, Tao-Yun Wang, Yao-Wu Liu
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218382428