Characterization of the role of Samsn1 loss in multiple myeloma development

Abstract The protein SAMSN1 was recently identified as a putative tumor suppressor in multiple myeloma, with re‐expression of Samsn1 in the 5TGM1/KaLwRij murine model of myeloma leading to a near complete abrogation of intramedullary tumor growth. Here, we sought to clarify the mechanism underlying...

Full description

Bibliographic Details
Main Authors: Natasha L. Friend, Duncan R. Hewett, Vasilios Panagopoulos, Jacqueline E. Noll, Kate Vandyke, Krzysztof M. Mrozik, Stephen Fitter, Andrew C.W. Zannettino
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2020-00027