YAP/TAZ Activation as a Target for Treating Metastatic Cancer

Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ) have both emerged as important drivers of cancer progression and metastasis. YAP and TAZ are often upregulated or nuclear localized in aggressive human cancers. There is abundant experimental evidence demonstr...

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Bibliographic Details
Main Authors: Janine S. A. Warren, Yuxuan Xiao, John M. Lamar
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Cancers
Subjects:
YAP
TAZ
Online Access:http://www.mdpi.com/2072-6694/10/4/115