YAP/TAZ Activation as a Target for Treating Metastatic Cancer
Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ) have both emerged as important drivers of cancer progression and metastasis. YAP and TAZ are often upregulated or nuclear localized in aggressive human cancers. There is abundant experimental evidence demonstr...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-04-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/4/115 |