The anti-microbial peptide TP359 attenuates inflammation in human lung cells infected with Pseudomonas aeruginosa via TLR5 and MAPK pathways.

The anti-microbial peptide TP359 attenuates inflammation in human lung cells infected with Pseudomonas aeruginosa via TLR5 and MAPK pathways.

Pseudomonas aeruginosa infection induces vigorous inflammatory mediators secreted by epithelial cells, which do not necessarily eradicate the pathogen. Nonetheless, it reduces lung function due to significant airway damage, most importantly in cystic fibrosis patients. Recently, we published that TP...

Full description

Bibliographic Details
Main Authors: Ejovwoke F Dosunmu, Robert O Emeh, Saurabh Dixit, Mona K Bakeer, Mamie T Coats, Donald R Owen, Shreekumar R Pillai, Shree R Singh, Vida A Dennis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5415104?pdf=render

Internet

http://europepmc.org/articles/PMC5415104?pdf=render

Similar Items