CXCR4+ cells are increased in lung tissue of patients with idiopathic pulmonary fibrosis

CXCR4+ cells are increased in lung tissue of patients with idiopathic pulmonary fibrosis

Abstract Background CXCR4, a transmembrane-receptor located on epithelial cells that is activated by CXCL12, may have a role in IPF via migration of CXCR4+ fibrocytes to the lung. However, its expression has not been fully characterised in idiopathic pulmonary fibrosis (IPF) or other fibrotic inters...

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Bibliographic Details
Main Authors: Jade Jaffar, Kate Griffiths, Sara Oveissi, Mubing Duan, Michael Foley, Ian Glaspole, Karen Symons, Louise Organ, Glen Westall
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Respiratory Research
Subjects:
CXCR4
CXCL12
Pulmonary fibrosis
Interstitial lung disease
Online Access:http://link.springer.com/article/10.1186/s12931-020-01467-0

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http://link.springer.com/article/10.1186/s12931-020-01467-0

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