Progression of oral squamous cell carcinoma accompanied with reduced E-cadherin expression but not cadherin switch.

The cadherin switch from E-cadherin to N-cadherin is considered as a hallmark of the epithelial-mesenchymal transition and progression of carcinomas. Although it enhances aggressive behaviors of adenocarcinoma cells, the significance and role of cadherin switch in squamous cell carcinomas (SCCs) are...

Full description

Bibliographic Details
Main Authors: Takashi Hashimoto, Yuichi Soeno, Genta Maeda, Yuji Taya, Takaaki Aoba, Masanori Nasu, Shuichi Kawashiri, Kazushi Imai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23110125/?tool=EBI