A model of Salmonella colitis with features of diarrhea in SLC11A1 wild-type mice.
Mice do not get diarrhea when orally infected with S. enterica, but pre-treatment with oral aminoglycosides makes them susceptible to Salmonella colitis. However, genetically susceptible ItyS mice (Nramp1(G169D) allele) die from systemic infection before they develop diarrhea, so a new model is need...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-02-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2225501?pdf=render |