Luminespib counteracts the Kifunensine-induced lung endothelial barrier dysfunction

Unfolded protein response (UPR) suppression by Kifunensine has been associated with lung hyperpermeability, the hallmark of Acute Respiratory Distress Syndrome. The present study investigates the effects of the heat shock protein 90 inhibitor Luminespib (AUY-922) towards the Kifunensine-triggered lu...

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Bibliographic Details
Main Authors: Khadeja-Tul Kubra, Mohammad A. Uddin, Mohammad S. Akhter, Nektarios Barabutis
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Current Research in Toxicology
Subjects:
P53
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X2030013X