Generation and characterization of cross neutralizing human monoclonal antibody against 4 serotypes of dengue virus without enhancing activity
Background Dengue disease is a leading cause of illness and death in the tropics and subtropics. Most severe cases occur among patients secondarily infected with a different dengue virus (DENV) serotype compared with that from the first infection, resulting in antibody-dependent enhancement activity...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-11-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4021.pdf |