FUT8-AS1 Inhibits the Malignancy of Melanoma Through Promoting miR-145-5p Biogenesis and Suppressing NRAS/MAPK Signaling

FUT8-AS1 Inhibits the Malignancy of Melanoma Through Promoting miR-145-5p Biogenesis and Suppressing NRAS/MAPK Signaling

Melanoma is the major lethal skin malignancy. However, the critical molecular drivers governing melanoma progression and prognosis are still not clear. By analyzing The Cancer Genome Atlas (TCGA) data, we identified FUT8-AS1 as a prognosis-related long non-coding RNA (lncRNA) in melanoma. We further...

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Bibliographic Details
Main Authors: Xiang-jun Chen, Sha Liu, Dong-mei Han, De-zhi Han, Wei-jing Sun, Xiao-chun Zhao, Jun-qing Liang, Li Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
FUT8-AS1
melanoma
malignancy
NF90
microRNA biogenesis
MAPK signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.586085/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.586085/full

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