Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer

<p>Abstract</p> <p>Background</p> <p>The HIV-1 Env glycoprotein mediates virus entry by catalyzing direct fusion between the virion membrane and the target cell plasma membrane. Env is composed of two subunits: gp120, which binds to CD4 and the coreceptor, and gp41, whi...

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Bibliographic Details
Main Authors: Salzwedel Karl, Berger Edward A
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/75