Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes

Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes

The Nod-like receptor 3 (NLRP3) inflammasome is an intracellular sensor that sets off the innate immune system in response to microbial-derived and endogenous metabolic danger signals. We previously reported that γ-tocotrienol (γT3) attenuated adipose tissue inflammation and insulin resistance in di...

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Bibliographic Details
Main Authors: Yongeun Kim, Wei Wang, Meshail Okla, Inhae Kang, Regis Moreau, Soonkyu Chung
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Lipid Research
Subjects:
inflammation
obesity
vitamin E
insulin signaling
diet and dietary lipids
NOD-like receptor protein 3
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314024

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http://www.sciencedirect.com/science/article/pii/S0022227520314024

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