Performance and impact of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® assays on tuberculosis case detection in Madagascar

Performance and impact of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® assays on tuberculosis case detection in Madagascar

Abstract Background Tuberculosis rapid molecular assays, including GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit®, are highly sensitive and specific. Such performance does not automatically translate in improved disease control and highly depends on their use, local epidemiology and the diagnost...

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Bibliographic Details
Main Authors: Niaina Rakotosamimanana, Simon Grandjean Lapierre, Vaomalala Raharimanga, Mamy Serge Raherison, Astrid M. Knoblauch, Antso Hasina Raherinandrasana, Andrianantenaina Rakotoson, Julio Rakotonirina, Voahangy Rasolofo
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
Loop-mediated isothermal amplification
GeneXpert
Case detection
Molecular diagnostics
Online Access:http://link.springer.com/article/10.1186/s12879-019-4198-6

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http://link.springer.com/article/10.1186/s12879-019-4198-6

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