MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells

Summary: All forms of diabetes mellitus (DM) are characterized by the loss of functional pancreatic β cell mass, leading to insufficient insulin secretion. Thus, identification of novel approaches to protect and restore β cells is essential for the development of DM therapies. Mesencephalic astrocyt...

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Bibliographic Details
Main Authors: Maria Lindahl, Tatiana Danilova, Erik Palm, Päivi Lindholm, Vootele Võikar, Elina Hakonen, Jarkko Ustinov, Jaan-Olle Andressoo, Brandon K. Harvey, Timo Otonkoski, Jari Rossi, Mart Saarma
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714002010