A DNA Repair and Cell Cycle Gene Expression Signature in Pediatric High-Grade Gliomas: Prognostic and Therapeutic Value
Background: Pediatric high-grade gliomas (pHGGs) are the leading cause of mortality in pediatric neuro-oncology, displaying frequent resistance to standard therapies. Profiling DNA repair and cell cycle gene expression has recently been proposed as a strategy to classify adult glioblastomas. To impr...
Main Authors: | Natacha Entz-Werlé, Laetitia Poidevin, Petr V. Nazarov, Olivier Poch, Benoit Lhermitte, Marie Pierre Chenard, Hélène Burckel, Eric Guérin, Quentin Fuchs, David Castel, Georges Noel, Laurence Choulier, Monique Dontenwill, Eric Van Dyck |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/9/2252 |
Similar Items
-
Strategic combination of DNA damaging agent and PARP inhibitor results in enhanced cytotoxicity
by: Julie K. Horton, et al.
Published: (2013-09-01) -
Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin
by: Zhiwei Zhang, et al.
Published: (2019-01-01) -
Polymorphism of the DNA Base Excision Repair Genes in Keratoconus
by: Katarzyna A. Wojcik, et al.
Published: (2014-10-01) -
Polymorphisms in DNA Repair Genes and Susceptibility to Glioma in a Chinese Population
by: Jun-Hong Guan, et al.
Published: (2013-02-01) -
Association of XRCC1, XRCC2 and XRCC3 Gene Polymorphism with Esophageal Cancer Risk
by: Kaur J, et al.
Published: (2020-03-01)