Mycobacterium tuberculosis Zinc Metalloprotease-1 Elicits Tuberculosis-specific Humoral Immune Response Independent of Mycobacterial Load in Pulmonary and Extra-Pulmonary Tuberculosis Patients

Mycobacterium tuberculosis Zinc Metalloprotease-1 Elicits Tuberculosis-specific Humoral Immune Response Independent of Mycobacterial Load in Pulmonary and Extra-Pulmonary Tuberculosis Patients

Conventionally, facultative intracellular pathogen, Mycobacterium tuberculosis (M.tb), the tuberculosis (TB) causing bacilli in human is cleared by cell-mediated immunity (CMI) with CD4+ T cells playing instrumental role in protective immunity, while antibody-mediated immunity (AMI) is considered no...

Full description

Bibliographic Details
Main Authors: Mani Harika eVemula, Rakesh eGanji, Ramya eSivangala, Kiran eJakkala, Sumanlatha eGaddam, Raju eP S, Sharmistha eBanerjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Microbiology
Subjects:
humoral immunity
tuberculosis (TB)
Pulmonary tuberculosis (PTB)
Extra-pulmonary tuberculosis (EPTB)
Rv0198c
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00418/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00418/full

Similar Items