Aging affects the transcriptional regulation of human skeletal muscle disuse atrophy.

Important insights concerning the molecular basis of skeletal muscle disuse-atrophy and aging related muscle loss have been obtained in cell culture and animal models, but these regulatory signaling pathways have not previously been studied in aging human muscle. In the present study, muscle atrophy...

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Bibliographic Details
Main Authors: Charlotte Suetta, Ulrik Frandsen, Line Jensen, Mette Munk Jensen, Jakob G Jespersen, Lars G Hvid, Monika Bayer, Stine J Petersson, Henrik D Schrøder, Jesper L Andersen, Katja M Heinemeier, Per Aagaard, Peter Schjerling, Michael Kjaer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526599?pdf=render