Apatinib treatment for KIT- and KDR-amplified angiosarcoma: a case report

Abstract Background Metastatic or relapsed angiosarcoma has a poor prognosis and the efficacy of conventional chemotherapy is often limited. Apatinib, a novel tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptor-2 (VEGFR2), has been approved for the treatment of adva...

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Bibliographic Details
Main Authors: Lishu Yang, Lizhu Liu, Bo Han, Wei Han, Meng Zhao
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
KDR
Online Access:http://link.springer.com/article/10.1186/s12885-018-4523-2