Common and Rare Variants Genetic Association Analysis of Circulating Neutrophil Extracellular Traps

IntroductionNeutrophils contribute to host defense through different mechanisms, including the formation of neutrophil extracellular traps (NETs). The genetic background and underlying mechanisms contributing to NET formation remain unclear.Materials and MethodsWe performed a genome-wide association...

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Bibliographic Details
Main Authors: Samantha J. Donkel, Eliana Portilla Fernández, Shahzad Ahmad, Fernando Rivadeneira, Frank J. A. van Rooij, M. Arfan Ikram, Frank W. G. Leebeek, Moniek P. M. de Maat, Mohsen Ghanbari
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.615527/full