Abnormal keratinocyte differentiation in the nasal planum of Labrador Retrievers with hereditary nasal parakeratosis (HNPK).

Abnormal keratinocyte differentiation in the nasal planum of Labrador Retrievers with hereditary nasal parakeratosis (HNPK).

Hereditary nasal parakeratosis (HNPK) is an inherited disorder described in Labrador Retrievers and Greyhounds. It has been associated with breed-specific variants in the SUV39H2 gene encoding a histone 3 methyltransferase involved in epigenetic silencing. Formalin-fixed biopsies of the nasal planum...

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Main Authors: Jeanette Bannoehr, Pierre Balmer, Michael H Stoffel, Vidhya Jagannathan, Véronique Gaschen, Kathrin Kühni, Beyza Sayar, Michaela Drögemüller, Denise Howald, Dominique J Wiener, Tosso Leeb, Monika M Welle, Eliane J Müller, Petra J Roosje
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225901

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https://doi.org/10.1371/journal.pone.0225901

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