Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina.

BACKGROUND: There is accumulating evidence that autoimmune components, such as autoantibodies and autoantibody depositions, play a role in the pathogenesis of neurodegenerative diseases like Alzheimeŕs disease or Multiple Sclerosis. Due to alterations of autoantibody patterns in sera and aqueous hum...

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Bibliographic Details
Main Authors: Oliver W Gramlich, Sabine Beck, Nadine von Thun Und Hohenstein-Blaul, Nils Boehm, Anika Ziegler, Jan M Vetter, Norbert Pfeiffer, Franz H Grus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3581473?pdf=render