Precise location of linear epitopes on the capsid surface of feline calicivirus recognized by neutralizing and non-neutralizing monoclonal antibodies

Abstract We report the generation, characterization and epitope mapping of a panel of 26 monoclonal antibodies (MAbs) against the VP1 capsid protein of feline calicivirus (FCV). Two close but distinct linear epitopes were identified at the capsid outermost surface (P2 subdomain) of VP1, within the E...

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Bibliographic Details
Main Authors: Carolina Cubillos-Zapata, Iván Angulo, Horacio Almanza, Belén Borrego, María Zamora-Ceballos, José R. Castón, Ignacio Mena, Esther Blanco, Juan Bárcena
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-020-00785-x