ZP4 confers structural properties to the zona pellucida essential for embryo development

Zona pellucida (ZP), the extracellular matrix sheltering mammalian oocytes and embryos, is composed by 3 to 4 proteins. The roles of the three proteins present in mice have been elucidated by KO models, but the function of the fourth component (ZP4), present in all other eutherian mammals studied so...

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Bibliographic Details
Main Authors: Ismael Lamas-Toranzo, Noelia Fonseca Balvís, Ana Querejeta-Fernández, María José Izquierdo-Rico, Leopoldo González-Brusi, Pedro L Lorenzo, Pilar García-Rebollar, Manuel Avilés, Pablo Bermejo-Álvarez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
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Online Access:https://elifesciences.org/articles/48904