Leishmania amazonensis promastigotes in 3D Collagen I culture: an in vitro physiological environment for the study of extracellular matrix and host cell interactions

Leishmania amazonensis is the causative agent of American cutaneous leishmaniasis, an important neglected tropical disease. Once Leishmania amazonensis is inoculated into the human host, promastigotes are exposed to the extracellular matrix (ECM) of the dermis. However, little is known about the int...

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Bibliographic Details
Main Authors: Debora B. Petropolis, Juliany C.F. Rodrigues, Nathan B. Viana, Bruno Pontes, Camila F.A. Pereira, Fernando C. Silva-Filho
Format: Article
Language:English
Published: PeerJ Inc. 2014-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/317.pdf