Luteoloside suppresses proliferation and metastasis of hepatocellular carcinoma cells by inhibition of NLRP3 inflammasome.

Luteoloside suppresses proliferation and metastasis of hepatocellular carcinoma cells by inhibition of NLRP3 inflammasome.

The inflammasome is a multi-protein complex which when activated regulates caspase-1 activation and IL-1β secretion. Inflammasome activation is mediated by NLR proteins that respond to stimuli. Among NLRs, NLRP3 senses the widest array of stimuli. NLRP3 inflammasome plays an important role in the de...

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Bibliographic Details
Main Authors: Shao-hua Fan, Yan-yan Wang, Jun Lu, Yuan-lin Zheng, Dong-mei Wu, Meng-qiu Li, Bin Hu, Zi-feng Zhang, Wei Cheng, Qun Shan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3935965?pdf=render

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http://europepmc.org/articles/PMC3935965?pdf=render

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