Protective Effect of SIRT1 Activator on the Knee With Osteoarthritis

Protective Effect of SIRT1 Activator on the Knee With Osteoarthritis

Osteoarthritis (OA), one of the most common chronic musculoskeletal disorders, is deemed to be correlated with aging. The SIRT1 activator, resveratrol, acts as a crucial regulator of aging and may have a potential therapeutic effect on OA. Rabbit OA models were established through destabilized media...

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Bibliographic Details
Main Authors: Zhenquan Zhou, Zhenhan Deng, Yuwei Liu, Yizi Zheng, Shiwei Yang, Wei Lu, Deming Xiao, Weimin Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
osteoarthritis
resveratrol
SIRT1
p53
cartilage
Micro-CT
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.661852/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.661852/full

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