The Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous Lesions

The Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous Lesions

The SOX2 gene located at 3q26 is frequently amplified and overexpressed in multiple cancers, including head and neck squamous cell carcinomas (HNSCC). The tumor-promoting activity and involvement of SOX2 in tumor progression has been extensively demonstrated, thereby emerging as a promising therapeu...

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Bibliographic Details
Main Authors: Rocío Granda-Díaz, Sofía T. Menéndez, Daniel Pedregal Mallo, Francisco Hermida-Prado, René Rodríguez, Laura Suárez-Fernández, Aitana Vallina, Mario Sánchez-Canteli, Aida Rodríguez, M. Soledad Fernández-García, Juan P. Rodrigo, Juana M. García-Pedrero
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
cancer risk assessment
larynx
dysplasia
SOX2
immunohistochemistry
gene amplification
Online Access:http://www.mdpi.com/2072-6694/11/3/286

Internet

http://www.mdpi.com/2072-6694/11/3/286

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