High-Density Lipoprotein (HDL) Inhibits Serum Amyloid A (SAA)-Induced Vascular and Renal Dysfunctions in Apolipoprotein E-Deficient Mice

High-Density Lipoprotein (HDL) Inhibits Serum Amyloid A (SAA)-Induced Vascular and Renal Dysfunctions in Apolipoprotein E-Deficient Mice

Serum amyloid A (SAA) promotes endothelial inflammation and dysfunction that is associated with cardiovascular disease and renal pathologies. SAA is an apoprotein for high-density lipoprotein (HDL) and its sequestration to HDL diminishes SAA bioactivity. Herein we investigated the effect of co-suppl...

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Bibliographic Details
Main Authors: Xiaoping Cai, Gulfam Ahmad, Farjaneh Hossain, Yuyang Liu, XiaoSuo Wang, Joanne Dennis, Ben Freedman, Paul K. Witting
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
renal inflammation
atherosclerosis
acute phase protein
oxidative damage
Online Access:https://www.mdpi.com/1422-0067/21/4/1316

Internet

https://www.mdpi.com/1422-0067/21/4/1316

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