Pharmacokinetic performance of the nitrendipine intravenous submicron emulsion in rats

To compare pharmacokinetic behaviors of nitrendipine submicron emulsion with nitrendipine solution following intravenous administration in rats. The plasma concentrations were analyzed by ultra-performance liquid chromatography coupled with tandem mass spectrometry detection (UPLC–MS/MS) through a n...

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Bibliographic Details
Main Authors: Jibin Guan, Nana Zhao, Yinglei Zhai, Chunxia Chu, Hongming Chen, Tianhong Zhang
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087614000592