BMI1 polycomb group protein acts as a master switch for growth and death of tumor cells: regulates TCF4-transcriptional factor-induced BCL2 signaling.

BMI1 polycomb group protein acts as a master switch for growth and death of tumor cells: regulates TCF4-transcriptional factor-induced BCL2 signaling.

For advanced prostate cancer (CaP), the progression of tumors to the state of chemoresistance and paucity of knowledge about the mechanism of chemoresistance are major stumbling blocks in the management of this disease. Here, we provide compelling evidence that BMI1 polycomb group protein and a stem...

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Bibliographic Details
Main Authors: Hifzur Rahman Siddique, Aijaz Parray, Rohinton S Tarapore, Lei Wang, Hasan Mukhtar, R Jeffery Karnes, Yibin Deng, Badrinath R Konety, Mohammad Saleem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3645992?pdf=render

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http://europepmc.org/articles/PMC3645992?pdf=render

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