Prevalence of methylenetetrahydrofolate reductase gene polymorphisms (C677T, and A1298C) among Saudi children receiving dental treatment

BACKGROUND: Methylenetetrahydrofolate reductase, the encoded by the MTHFR gene, plays a crucial role in converting the amino acid homocysteine to methionine. Two polymorphisms of the MTHFR gene, C677T and A1298C, reportedly reduce enzyme activity, resulting in hyperhomocysteinemia. Patients with C67...

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Bibliographic Details
Main Authors: Amina M. Bagher, Alexander P. Young, Thikryat Neamatallah, Reham M. Al-Amoudi, Sara M. Bagher, Eileen M. Denovan-Wright
Format: Article
Language:English
Published: King Faisal Specialist Hospital and Research Centre 2021-02-01
Series:Annals of Saudi Medicine
Online Access:https://www.annsaudimed.net/doi/full/10.5144/0256-4947.2021.1