Effectors of the spindle assembly checkpoint are confined within the nucleus of Saccharomyces cerevisiae

The spindle assembly checkpoint (SAC) prevents erroneous chromosome segregation by delaying mitotic progression when chromosomes are incorrectly attached to the mitotic spindle. This delay is mediated by mitotic checkpoint complexes (MCCs), which assemble at unattached kinetochores and repress the a...

Full description

Bibliographic Details
Main Authors: Lydia R. Heasley, Jennifer G. DeLuca, Steven M. Markus
Format: Article
Language:English
Published: The Company of Biologists 2019-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/6/bio037424