Berberine Activates Aryl Hydrocarbon Receptor but Suppresses CYP1A1 Induction through miR-21-3p Stimulation in MCF-7 Breast Cancer Cells

Berberine Activates Aryl Hydrocarbon Receptor but Suppresses CYP1A1 Induction through miR-21-3p Stimulation in MCF-7 Breast Cancer Cells

Berberine and the methylenedioxy ring-opening derivatives palmatine and jatrorrhizine are active ingredients in immunomodulatory plants, such as goldenseal. This study aimed to illustrate the effects of protoberberines on aryl hydrocarbon receptor (AhR) activation and cytochrome P450 (CYP) 1 in the...

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Bibliographic Details
Main Authors: Sheng-Nan Lo, Chun-Wei Wang, Yueh-Shieh Chen, Chiung-Chiao Huang, Tian-Shung Wu, Lih-Ann Li, I-Jung Lee, Yune-Fang Ueng
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
berberine
aryl hydrocarbon receptor
CYP1A1
miR-21-3p
breast cancer cells
Online Access:https://www.mdpi.com/1420-3049/22/11/1847

Internet

https://www.mdpi.com/1420-3049/22/11/1847

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