Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy.

Diabetic nephropathy (DNP) is a common complication of type 1 and type 2 diabetes mellitus and the most common cause of kidney failure. While DNP manifests with albuminuria and diabetic glomerulopathy, its progression correlates best with tubular epithelial degeneration (TED) and interstitial fibros...

Full description

Bibliographic Details
Main Authors: Katalin Susztak, Emilio Ciccone, Peter McCue, Kumar Sharma, Erwin P Böttinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-02-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC549593?pdf=render