Nitric Oxide (NO) and Duchenne Muscular Dystrophy: NO Way to Go?

Nitric Oxide (NO) and Duchenne Muscular Dystrophy: NO Way to Go?

The discordance between pre-clinical success and clinical failure of treatment options for Duchenne Muscular Dystrophy (DMD) is significant. The termination of clinical trials investigating the phosphodiesterase inhibitors, sildenafil and tadalafil (which prolong the second messenger molecule of nit...

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Bibliographic Details
Main Authors: Cara A. Timpani, Kamel Mamchaoui, Gillian Butler-Browne, Emma Rybalka
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
Duchenne muscular dystrophy
metabolism
nitric oxide
nitrite
reactive oxygen species
superoxide
Online Access:https://www.mdpi.com/2076-3921/9/12/1268

Internet

https://www.mdpi.com/2076-3921/9/12/1268

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