Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2

Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2

ObjectiveThis study aimed to describe the mechanism of exosome-derived miR-486-5p underlying the cell cycle and progression in lung adenocarcinoma (LUAD).MethodsBioinformatics methods were applied for identifying the differentially expressed genes (DEGs) in the GEO-LUAD dataset, predicting where the...

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Bibliographic Details
Main Authors: Huihui Hu, Hangdi Xu, Fen Lu, Jisong Zhang, Li Xu, Shan Xu, Hanliang Jiang, Qingxin Zeng, Enguo Chen, Zhengfu He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
miR-486-5p
NEK2
lung adenocarcinoma
proliferation
migration and invasion
cell cycle
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00259/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00259/full

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