Tryptophan Metabolic Pathways Are Altered in Obesity and Are Associated With Systemic Inflammation

Tryptophan Metabolic Pathways Are Altered in Obesity and Are Associated With Systemic Inflammation

Background: Obesity is a condition with a complex pathophysiology characterized by both chronic low-grade inflammation and changes in the gut microbial ecosystem. These alterations can affect the metabolism of tryptophan (TRP), an essential amino acid and precursor of serotonin (5-HT), kynurenine (K...

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Bibliographic Details
Main Authors: Sofia Cussotto, Inês Delgado, Andrea Anesi, Sandra Dexpert, Agnès Aubert, Cédric Beau, Damien Forestier, Patrick Ledaguenel, Eric Magne, Fulvio Mattivi, Lucile Capuron
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
obesity
inflammation
tryptophan
kynurenine
indoles
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00557/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00557/full

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