Oxidative stress induces caveolin 1 degradation and impairs caveolae functions in skeletal muscle cells.

Increased level of oxidative stress, a major actor of cellular aging, impairs the regenerative capacity of skeletal muscle and leads to the reduction in the number and size of muscle fibers causing sarcopenia. Caveolin 1 is the major component of caveolae, small membrane invaginations involved in si...

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Bibliographic Details
Main Authors: Alexis Mougeolle, Sylvie Poussard, Marion Decossas, Christophe Lamaze, Olivier Lambert, Elise Dargelos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370508?pdf=render