Co-regulation of pluripotency and genetic integrity at the genomic level

The Disposable Soma Theory holds that genetic integrity will be maintained at more pristine levels in germ cells than in somatic cells because of the unique role germ cells play in perpetuating the species. We tested the hypothesis that the same concept applies to pluripotent cells compared to diff...

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Bibliographic Details
Main Authors: Daniel J. Cooper, Christi A. Walter, John R. McCarrey
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114001081