Correlation of MRI Biomarkers with Tumor Necrosis in Hras5 Tumor Xenograft in Athymic Rats

Magnetic resonance imaging (MRI) can measure the effects of therapies targeting the tumor vasculature and has demonstrated that vascular-damaging agents (VDA) induce acute vascular shutdown in tumors in human and animal models. However, at subtherapeutic doses, blood flow may recover before the ind...

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Bibliographic Details
Main Authors: Daniel P. Bradley, Jean J. Tessier, Susan E. Ashton, John C. Waterton, Zena Wilson, Philip L. Worthington, Anderson J. Ryan
Format: Article
Language:English
Published: Elsevier 2007-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800881