Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension

Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension

A significant glycolytic shift in the cells of the pulmonary vasculature and right ventricle during pulmonary arterial hypertension (PAH) has been recently described. Due to the late complications and devastating course of any variant of this disease, there is a great need for animal models that rep...

Full description

Bibliographic Details
Main Authors: Jose L. Izquierdo-Garcia, Teresa Arias, Yeny Rojas, Victoria Garcia-Ruiz, Arnoldo Santos, Silvia Martin-Puig, Jesus Ruiz-Cabello
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
pulmonary arterial hypertension
metabolomics
preclinical models
molecular imaging
NMR spectroscopy
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00110/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2018.00110/full

Similar Items