A genome-wide association study of pulmonary function measures in the Framingham Heart Study.

The ratio of forced expiratory volume in one second to forced vital capacity (FEV(1)/FVC) is a measure used to diagnose airflow obstruction and is highly heritable. We performed a genome-wide association study in 7,691 Framingham Heart Study participants to identify single-nucleotide polymorphisms (...

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Bibliographic Details
Main Authors: Jemma B Wilk, Ting-Hsu Chen, Daniel J Gottlieb, Robert E Walter, Michael W Nagle, Brian J Brandler, Richard H Myers, Ingrid B Borecki, Edwin K Silverman, Scott T Weiss, George T O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2652834?pdf=render