Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D).

Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D).

The recombinant circumsporozoite protein (CS) based vaccine, RTS,S, confers protection against Plasmodium falciparum infection in controlled challenge trials and in field studies. The RTS,S recombinant antigen has been formulated with two adjuvant systems, AS01 and AS02, which have both been shown t...

Full description

Bibliographic Details
Main Authors: Selidji T Agnandji, Rolf Fendel, Michaël Mestré, Michel Janssens, Johan Vekemans, Jana Held, Ferdinand Gnansounou, Sonja Haertle, Isabel von Glasenapp, Sunny Oyakhirome, Ludovic Mewono, Philippe Moris, Marc Lievens, Marie-Ange Demoitie, Patrice M Dubois, Tonya Villafana, Erik Jongert, Aurelie Olivier, Joe Cohen, Meral Esen, Peter G Kremsner, Bertrand Lell, Benjamin Mordmüller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3073948?pdf=render

Internet

http://europepmc.org/articles/PMC3073948?pdf=render

Similar Items